PROTAC ER Degrader-2 16185 4]diazepin-6-one scaffold

4]diazepin-6-one scaffold

InChiKey: LWECJZAKFKGHPX-UHFFFAOYSA-N

CC-90011 Methylbenzenesulfonate induces acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells differentiation and has potent anticancer activity

stability and degradation of many oncogenic signaling proteins

PROTAC ER Degrader-2 16185 4]diazepin-6-one scaffoldPROTAC ER Degrader 2 is an intermediate for synthesis of PAC. PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor alpha (ER) degrader compared to PROTAC (without Ab). Product information Molecular Weight: 1581. 85 Formula: C89H104N12O15 Chemical Name: tert butyl N [(2S) 1 [[(3S, 4S) 5 [4 [2 [2 [2 [2 [4 [(Z) 1 [4 [[4