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and antitumor activities
Tyrphostin AG 112 is an EGFR phosphorylation inhibitor
The two Endomorphins display reasonable affinities for kappa3 binding sites
17(2):261-6
APC 366 de-O-amido-C8-NH2 hydrochloride and antitumor activitiesAPC 366 is a selective and competitive inhibitor of tryptase [1, 2, 3]. After about 4 h of incubation with human tryptase, APC 366 showed an inhibitory potential with a Ki value of 530 nM and an IC50 value of 1400 240 nM . Tryptase is a mast cell serine protease. It had been implicated in the allergic asthma pathophysiology . It seemed that actions of tryptase were dependent on an intact catalytic site. APC 366 inhibited DNA synthesis and the
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