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Chemical Name: 2-methyl-1-((4-(6-(trifluoromethyl)pyridin-2-yl)-6-((2-(trifluoromethyl)pyridin-4-yl)amino)-1
GDC-0941 was used at 1-10 µM in vitro and in cellular assays
Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design
Chemical Name: 1-acryloyl-3
5-Hydroxymethyldeoxyuridine - CAS# 5116-24-5 180 Chemical Name: 2-methyl-1-((4-(6-(trifluoromethyl)pyridin-2-yl)-6-((2-(trifluoromethyl)pyridin-4-yl)amino)-15 Hydroxymethyldeoxyuridine, CAS No. 5116 24 5, is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8. 5 and 4 M, respectively) and multiple human leukemia cell lines (IC50s = 1. 7 5. 8 M). Product information CAS Number: 5116 24 5 Molecular Weight: 258. 23 Formula: C10H14N2O6 Synonym: 5 Hydroxymethyl 2' deoxyuridine
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