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and leads to further increases in airways hyperresponsiveness
Emixustat potently inhibits isomerase activity in vitro (IC50=4
01-1000 μM) produces a concentration-dependent relaxation of phenylephrine-preconstricted isolated mesenteric arteries and causes full relaxation with 1 mM
InChi: InChI=1S/C26H37N5O5S/c1-16-22(37-15-29-16)18-7-5-17(6-8-18)12-28-24(34)20-11-19(32)13-31(20)25(35)23(26(2
MF-438 Size:2mg solid and leads to further increasesMF 438 is a potent and orally bioavailable stearoyl CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2. 3 nM for rSCD1. Product information CAS Number: 921605 87 0 Molecular Weight: 421. 44 Formula: C19H18F3N5OS Chemical Name: 3 (5 methyl 1,3,4 thiadiazol 2 yl) 6 {4 [2 (trifluoromethyl)phenoxy]piperidin 1 yl}pyridazine Smiles: CC1=NN=C(S1)C1C=CC(=NN=1)N1CCC(CC1)OC1=CC=CC=C1C(F)(F)F InChiKey: NVUJDKDVOZVALT UHFFFAOYSA N InChi: InChI=1S C19H18F3N5OS c1