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Rosiglitazone-d3 Catalog No.:M24882-C 48)12-11-33(45)39-23-7-9-27-20(13-23)15-29(41-27)35(46)40-24-8-10-28-21(14-24)16-30(42-28)36(47)43-19-22(18-38)34-26-6-4-3-5-25(26)32(44)17-31(34)43/h3-10

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48)12-11-33(45)39-23-7-9-27-20(13-23)15-29(41-27)35(46)40-24-8-10-28-21(14-24)16-30(42-28)36(47)43-19-22(18-38)34-26-6-4-3-5-25(26)32(44)17-31(34)43/h3-10

resulting in the inhibition of tumor angiogenesis

84:185-190

Tilman Läppchen

Rosiglitazone-d3 Catalog No.:M24882-C 48)12-11-33(45)39-23-7-9-27-20(13-23)15-29(41-27)35(46)40-24-8-10-28-21(14-24)16-30(42-28)36(47)43-19-22(18-38)34-26-6-4-3-5-25(26)32(44)17-31(34)43/h3-10Rosiglitazone d3 (BRL 49653 d3) is the deuterium labeled Rosiglitazone. Rosiglitazone (BRL 49653) is a selective, orally active PPAR agonist with EC50s of 30 nM, 100 nM and 60 nM for PPAR1, PPAR2, and PPAR, respectively. Rosiglitazone binds to PPAR with a Kd of approximately 40 nM. Rosiglitazone is also an activator of TRPC5 (EC50=~30 M) and an inhibitor of TRPM3. Product information CAS Number: 1132641 22 5 Molecular Weight: 360. 45 Formula:

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