Pay in 4 interest-free payments of $28.50 Learn more
Ships within 48 hours · Estimated delivery Aug 1 - Aug 6
GW3965 dose-dependently regulates lps-mediated liver injury and modulates posttranscriptional TNF-alpha production and p38 mitogen-activated protein kinase activation in liver macrophages
InChi: InChI=1S/C15H11ClN2OS/c16-11-3-1-10(2-4-11)14-9-20-15(18-14)17-12-5-7-13(19)8-6-12/h1-9
InChiKey: USMZPYXTVKAYST-UHFFFAOYSA-N
J Nucl Med
A 438079 Hydrochloride - CAS# 899431-18-6 Size:Solid 10 mg GW3965 dose-dependently regulates lps-mediated liverA 438079 is a P2X7 receptor antagonist. A438079 protects against acetaminophen induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation. A 438079 partially but significantly prevented the 6 OHDA induced depletion of striatal DA stores. P2X7R inhibitor A 438079 reduced electrographic and clinical seizure severity during status epilepticus and reduced seizure induced neuronal death in the neocortex. Blockade of P2X(7) receptors
US$ 42.00
US$ 69.95
US$ 69.95
US$ 79.95