Cilomilast-d9 ide D Smiles: CCCCCCC/C=C\[C@H](O)C#CC#C[C@H](O)C=C

Smiles: CCCCCCC/C=C\[C@H](O)C#CC#C[C@H](O)C=C

a fodder additive for poultry

Such an increase is significantly reduced by administration of INF39 (+2

Hopkins CR

Cilomilast-d9 ide D Smiles: CCCCCCC/C=C\[C@H](O)C#CC#C[C@H](O)C=CCilomilast d9 (SB 207499 d9) is the deuterium labeled Cilomilast. Cilomilast (SB 207499) is a potent, selective and orally active inhibitor of Phosphodiesterase 4 (PDE4), with IC50s of ~100 and 120 nM for LPDE4 and HPDE4, respectively. Cilomilast shows selectivity for PDE4 over PDE1, PDE2, PDE3 and PDE5 (IC50=74, 65, >100, and 83 M, respectively). Cilomilast has anti inflammatory and immunomodulatory effects and can be used for thr research of asthma