L-873724 ressin acetate 19-tetraoxa-4

19-tetraoxa-4

Smiles: OC[C@H]1O[C@H]([C@@H](O)[C@@H]1O)N1C=CC(=O)NC1=O

Phoyunnanin E down-regulates integrins αv and β3 and the regulatory proteins in cell migration

Oral administration of ZSTK474 inhibits the growth of subcutaneously implanted mouse B16F10 melanoma tumors in a dose-dependent manner

L-873724 ressin acetate 19-tetraoxa-4L 873724 is a potent, orally bioavailable, selective and reversible non basic cathepsin K inhibitor, with IC50s of 0. 2, 178, 264, and 5239 nM for cathepsin K, cathepsin S, cathepsin L, cathepsin B, respectively. L 873724 also exhibits an IC50 of 0. 5 nM for rabbit cathepsin K. L 873724 inhibits bone resorption. Product information CAS Number: 603139 12 4 Molecular Weight: 481. 53 Formula: C23H26F3N3O3S Chemical Name: (2S) N (cyanomethyl) 4 methyl 2