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(2009) J Cell Sci
2007 Jan 2
Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3
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1-methyl-D-tryptophan (D-1MT) - IDO Inhibitor. CAS# 110117-83-4 size:2 mg solid (2009) J Cell Sci1 methyl D tryptophan (D 1MT) , CAS No. 110117 83 4, is a potent and selective indoleamine 2, 3 dioxygenase (IDO) inhibitor with IC50 ~7 M. It disrupts tryptophan catabolism and enhances the antitumor and antiviral immunoresponses of CD8+ T cells in vitro. It can reduce tumor volume in mice with xenografts overexpressing IDO. Product information CAS Number: 110117 83 4 Molecular Weight: 218. 25 Formula: C12H14N2O2 Synonym: D 1MT 1 MT 1 Methyl D