MHY1485 - mTOR Activator. CAS# 326914-06-1 Catalog No.:M60189-10S InChi: InChI=1S/C25H30N2O5/c1-15-21(24(29)32-18-7-5-4-6-8-18)22(16-9-11-17(12-10-16)27(30)31)23-19(26-15)13-25(2

Name: MHY1485 - mTOR Activator. CAS# 326914-06-1 Catalog No.:M60189-10S InChi: InChI=1S/C25H30N2O5/c1-15-21(24(29)32-18-7-5-4-6-8-18)22(16-9-11-17(12-10-16)27(30)31)23-19(26-15)13-25(2
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InChi: InChI=1S/C25H30N2O5/c1-15-21(24(29)32-18-7-5-4-6-8-18)22(16-9-11-17(12-10-16)27(30)31)23-19(26-15)13-25(2

(2001) Neurosci Lett 308: 37-40

(2015) PLoS One

125256-00-0

MHY1485 - mTOR Activator. CAS# 326914-06-1 Catalog No.:M60189-10S InChi: InChI=1S/C25H30N2O5/c1-15-21(24(29)32-18-7-5-4-6-8-18)22(16-9-11-17(12-10-16)27(30)31)23-19(26-15)13-25(2MHY1485, CAS No. 326914 06 1, is a novel potent, selective and cell permeable mTOR activator. It suppressed the basal autophagic flux, and this inhibitory effect was clearly confirmed in cells under starvation, a strong physiological inducer of autophagy. It can increase cellular mTOR Ser2448 and downstream substrate 4E BP Thr37 46 phosphorylation level in rat liver Ac2F cells (1 to 2 M for 1 h). It affects culture viability only at much higher

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