MRK-016 IA 6)7)13-17(2)27(34)30(38-20(5)33)14-18(3)26(24(30)25(16)36-19(4)32)37-28(35)21-9-8-12-31-15-21/h8-9

6)7)13-17(2)27(34)30(38-20(5)33)14-18(3)26(24(30)25(16)36-19(4)32)37-28(35)21-9-8-12-31-15-21/h8-9

CAS Number: 524-30-1

Deserpidine is used as an antihypertensive agent and a tranquilizer

STAT3 dimerization

MRK-016 IA 6)7)13-17(2)27(34)30(38-20(5)33)14-18(3)26(24(30)25(16)36-19(4)32)37-28(35)21-9-8-12-31-15-21/h8-9MRK 016 is a selective, orally bioavailable inverse agonist of GABAA 5 receptor, with an EC50 of 3 nM for GABAA 5, and Kis of 0. 83, 0. 85, 0. 77 and 1. 4 nM for human GABAA 132, GABAA 232, GABAA 332, and GABAA 532, respectively; MRK 016 also readily penetrates the CNS. Product information CAS Number: 342652 67 9 Molecular Weight: 368. 39 Formula: C17H20N8O2 Chemical Name: 5 ({[3 tert butyl 7 (5 methyl 1,2 oxazol 3 yl)pyrazolo[1,5 d][1,2,4]triazin 2