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InChiKey: SNYHHRDGEJPLGT-OJSHLMAWSA-L
is a activin receptor-like kinase-2 (ALK2) inhibitor extracted from patent WO2017181117A1
Formula: C13H8N2O3
InChi: InChI=1S/C20H27N3O2/c1-13-12-22(16-3-2-4-16)9-10-23(13)20(25)18-11-17(18)14-5-7-15(8-6-14)19(21)24/h5-8
Tyk2-IN-5 ino pyrazole InChiKey: SNYHHRDGEJPLGT-OJSHLMAWSA-LTyk2 IN 5 (compound 6) is a highly potent, selective and orally active Tyk2 inhibitor and targets the JH2 domain, with a Ki of 0. 086 nM for Tyk2 JH2 and an IC50 of 25 nM for IFN. Highly effective in inhibiting IFN production in a rat pharmacodynamics model and fully efficacious in a rat adjuvant arthritis model. Product information CAS Number: 1797432 62 2 Molecular Weight: 434. 43 Formula: C21H19FN8O2 Chemical Name: N [(1R,2S) 2 fluorocyclopropyl] 8
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