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MT-3014 xylosyltaxol GSK690 (1-10 μM) acts together

SKU: 54372725171

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Description

GSK690 (1-10 μM) acts together with JNJ-26481585 to induce cell death in all four tested RMS cells lines (RD

once) significantly inhibits eosinophil recruitment following antigen challenge in ovalbumin-sensitized guinea pigs

29(3):163-71

InChi: InChI=1S/C14H17N3S/c1-2-7-11-10(6-1)12-13(17-9-4-3-5-9)15-8-16-14(12)18-11/h8-9H

MT-3014 xylosyltaxol GSK690 (1-10 μM) acts togetherMT 3014 is a potent, highly selective and brain penetrated phosphodiesterase 10A (PDE 10A) inhibitor, with IC50s of 0. 062 nM and 0. 09 nM for human PDE 10A and bovine PDE 10A, respectively. Product information CAS Number: 1332727 40 8 Molecular Weight: 453. 49 Formula: C23H25F2N7O Chemical Name: 1 {[2 (7 fluoro 3 methylquinoxalin 2 yl) 5 [(3R) 3 fluoropyrrolidin 1 yl]pyrazolo[1,5 a]pyrimidin 7 yl]amino} 2 methylpropan 2 ol Smiles:

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