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Apilimod inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis
Currently it is approved by US FDA for relapsed and refractory multiple myeloma in 2012
brucei and that parasite Aurora kinases can be targeted with small-molecule inhibitors
The molecular targets of CE and DBZ are the N-terminal fragment of presenilin 1 within the γ-secretase complex
Roxindole hydrochloride lesteryl sulfate sodium Apilimod inhibits the production ofProduct information CAS Number: 108050 82 4 Molecular Weight: 382. 93 Formula: C23H27ClN2O Chemical Name: 3 [4 (4 phenyl 1,2,3,6 tetrahydropyridin 1 yl)butyl] 1H indol 5 ol hydrochloride Smiles: Cl. OC1C=C2C(=CC=1)NC=C2CCCCN1CC=C(CC1)C1C=CC=CC=1 InChiKey: ZCEPVNSWLLJECX UHFFFAOYSA N InChi: InChI=1S C23H26N2O. ClH c26 21 9 10 23 22(16 21)20(17 24 23)8 4 5 13 25 14 11 19(12 15 25)18 6 2 1 3 7 18; h1 3,6 7,9 11,16 17,24,26H,4 5,8,12 15H2; 1H Technical
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