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InChi: InChI=1S/C19H20N2O4S/c1-12(22)14-4-5-15(20-11-14)8-9-25-16-6-2-13(3-7-16)10-17-18(23)21-19(24)26-17/h2-7
CAS Number: 91433-17-9
but is highly selective with regard to other enzymes
1 or 3 mg/kg
Imatinib Impurity E PEG3-amine-Boc InChi: InChI=1S/C19H20N2O4S/c1-12(22)14-4-5-15(20-11-14)8-9-25-16-6-2-13(3-7-16)10-17-18(23)21-19(24)26-17/h2-7Imatinib Impurity E is the impurity of Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR ABL, v Abl, PDGFR and c kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively. Imatinib also is an inhibitor of SARS CoV and MERS CoV. Product