InChiKey: ALELTFCQZDXAMQ-XERRXZQWSA-N
primarily within Gram-positive bacteria
Smiles: NC1N=CN=C2OC=C(C2=1)C1=CC2CCN(C(=O)CC3=CC(F)=CC=C3F)C=2C=C1
Desmethyl Vc-seco-DUBA consists a cleavable ADC linker (Desmethyl Vc-seco) and a DNA alkylating agent (DUBA)
CJ-2360 Catalog No.:M33349-C InChiKey: ALELTFCQZDXAMQ-XERRXZQWSA-NCJ 2360 is a potent and orally active ALK inhibitor with IC50s of 2. 2, 4. 0, 8. 8, 6. 3, and 8. 9 nM against wild type ALK and F1197M, G1269A, L1196M, and S1206Y ALK mutants, respectively. CJ 2360 displays potent inhibitory activity against two clinically reported ALK mutants (C1156Y and L1196M) and a few other kinases (LTK, MERTK, CLK1, DAPK1, and DAPK2) among the 468 kinases evaluated. Product information CAS Number: 2226742 61 4 Molecular Weight: