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Aβ/tau aggregation-IN-1 with N-methylation of the quinolone ring effectively inhibits Aβ1-42 aggregation by 84
Chemical Name: 4-[(2-fluoro-4-methylphenyl)amino]-6-[4-(2-hydroxyethyl)piperazin-1-yl]-7-methoxycinnoline-3-carboxamide
Ciliobrevin A can block the proliferation of SmoM2-expressing CGNPs and should be equally potent against CGNPs lacking Su(fu) function
Formula: C9H15N5O3
WAY-213613 yl-PEG6-alcohol Aβ/tau aggregation-IN-1 with N-methylation ofWAY 213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT 1 EAAT2 with IC50 of 85 nM EAAT2. It displays 59 and 44 fold selectivity over EAAT1 and EAAT3 (IC50s are 5 and 3. 8 M, respectively). WAY 213613 shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function. Product information CAS Number: 868359 05 1 Molecular Weight: 415. 19 Formula: C16H13BrF2N2O4 Chemical
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