![Pirinixic Acid Aminothiazole l-PEG12-OH Smiles: [N-]=[N+]=N[C@H]1[C@H](CO)O[C@@H]([C@H]1O)N1C=CC(=O)NC1=O](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M22488_1635325144.gif?v=1635325146)
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Smiles: [N-]=[N+]=N[C@H]1[C@H](CO)O[C@@H]([C@H]1O)N1C=CC(=O)NC1=O
Formula: C16H13ClO4S
Bryonolic acid against N-methyl-D-aspartate (NMDA)-induced neurotoxicity
95(3):812-822
Pirinixic Acid Aminothiazole l-PEG12-OH Smiles: [N-]=[N+]=N[C@H]1[C@H](CO)O[C@@H]([C@H]1O)N1C=CC(=O)NC1=OPirinixic Acid Aminothiazole is a dual inhibitor of 5 lipoxygenase (5 LO) and microsomal prostaglandin E2 synthase 1 (mPGES 1) with IC50 values of 0. 3 and 0. 4 M, respectively . 5 lipoxygenase (5 LO) and microsomal prostaglandin E2 synthase 1 (mPGES 1) are critical enzymes involved in the metabolism of arachidonic acid (AA). They are key enzymes in the synthesis of leukotrienes (LTs) and PGE2, respectively . Dual inhibition of 5 LO and mPGES 1 is
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