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GNE-0723 Catalog No.:M13850-2 Chemical Name: 6-[6-(methoxymethyl)pyridin-3-yl]-4-{[1-(oxan-4-yl)ethyl]amino}quinoline-3-carboxamide

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Description

Chemical Name: 6-[6-(methoxymethyl)pyridin-3-yl]-4-{[1-(oxan-4-yl)ethyl]amino}quinoline-3-carboxamide

A partial inhibition of KDM7A toward both H3K9me2 and H3K27me2 peptides is observed in the presence of 50 mM D-2-HG and 100 μM α-ketoglutarate (α-KG)

Talabostat

as well as excellent selectivity in broader kinase profiling

GNE-0723 Catalog No.:M13850-2 Chemical Name: 6-[6-(methoxymethyl)pyridin-3-yl]-4-{[1-(oxan-4-yl)ethyl]amino}quinoline-3-carboxamideGNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7. 4 and 6. 2 M for GluN2C and GluN2D, respectively. Product information CAS Number: 1883518 31 7 Molecular Weight: 467. 78 Formula: C16H8ClF6N5OS Chemical Name: (1R,2R) 2 (7 {[5 chloro 3 (trifluoromethyl) 1H pyrazol 1 yl]methyl} 5 oxo 2 (trifluoromethyl) 5H [1,3]thiazolo[3,2 a]pyrimidin 3 yl)cyclopropane 1 carbonitrile Smiles:

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