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P5091 (P005091)
COH29 results in a dose-dependent inhibition of MOLT-4 tumor xenograft growth with twice-daily oral dosing at 50 mg/kg and 100 mg/kg
but failed to do it in rats on a normal calcium diet
2015 Apr 17
IQ-1S free acid Catalog No.:M12297-10 P5091 (P005091)IQ 1S free acid is a prospective inhibitor of NF B activating protein 1 (AP 1) activity with an IC50 of 2. 30. 41 M. IQ 1S free acid has binding affinity (Kd values) in the nanomolar range for all three JNKs with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively. Product information CAS Number: 23146 22 7 Molecular Weight: 247. 25 Formula: C15H9N3O Chemical Name: N [(11E) 11H indeno[1, 2 b]quinoxalin 11 ylidene]hydroxylamine