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Nutlin-C1-amido-PEG4-C2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Nutlin 3 based MDM2 ligand and 4-unit PEG linker used in PROTAC technology
Br-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs
GW501516 inhibits palmitate- and TNFα-induced increases in MCP-1 mRNA expression in a dose-dependent manner
Smiles: O=C1COCCN1C1C=CC(=CC=1)N1C[C@@H](CNC(=O)C2=CC=C(Cl)S2)OC1=O
Clenbuterol (hydrochloride) necionine Nutlin-C1-amido-PEG4-C2-N3 is a synthesized E3Clenbuterol is a sympathomimetic 2 adrenoceptor agonist. 2 adrenoceptor agonists, mainly long acting 2 adrenoceptor agonists, are an important pharmacological approach to induce bronchodilation in patients with chronic obstructive pulmonary disease. In vitro: A hormone dependent human breast cancer cell line was treated with different concentrations of clenbuterol. It was found that clenbuterol could stimulate cell proliferation at low concentrations,
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