Pay in 4 interest-free payments of $22.50 Learn more
Ships within 48 hours · Estimated delivery Aug 3 - Aug 8
EW-7197 prolongs the life span of BALB/c 4T1 mice via inhibition of EMT
Formula: C25H23BO4
demonstrates potent antimigratory and anti-invasive effects in vitro
CAS Number: 923359-38-0
Oclacitinib - CAS# 1208319-26-9 Catalog No.:M9848-2 EW-7197 prolongs the life spanOclacitinib, also known as PF03394197, is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Oclacitinib inhibited JAK family members by 50% at concentrations (IC50 's) ranging from 10 to 99 nM and did not inhibit a panel of 38 non JAK kinases (IC50 's > 1000 nm). Oclacitinib was most potent at inhibiting JAK1 (IC50 = 10 nm). Oclacitinib also inhibited the function of JAK1 dependent cytokines involved in allergy and