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selective and ATP-competitive cell division cycle 7 (CDC7) kinase inhibitor
A comparative study on essential oil components of wild and cultivated Atractylodes lancea and A
Formula: C27H36N8O5
Effect of a sigma-1 receptor agonist
DuP-697 rphostin A9 selective and ATP-competitive cell divisionDuP 697 is a member of the vicinal diaryl heterocycles and a potent, irreversible, selective and orally active COX 2 inhibitor (IC50 of 10 nM and 800 nM for human COX 2 and COX 1, respectively). DuP 697 exerts antiproliferative (IC50 of 42. 8 nM), antiangiogenic and apoptotic effects on HT29 colorectal cancer cells. DuP 697 inhibits prostaglandin synthesis and has anti inflammatory, anticancer and antipyretic effects. Product information CAS Number:
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