TrxR inhibitor D9 Size:2mg solid 3H-benzo[e]indole-3-carbonyl]-1H-indol-5-yl}-5-(4-methyl-4-sulfanylpentanamido)-1H-indole-2-carboxamide

3H-benzo[e]indole-3-carbonyl]-1H-indol-5-yl}-5-(4-methyl-4-sulfanylpentanamido)-1H-indole-2-carboxamide

degrades clinically relevant androgen receptor point mutants and unlike enzalutamide

5)6)37-32(44)39-21(2)13-12-14-22(39)3/h10-11

GSK650394 is relatively non-toxic

TrxR inhibitor D9 Size:2mg solid 3H-benzo[e]indole-3-carbonyl]-1H-indol-5-yl}-5-(4-methyl-4-sulfanylpentanamido)-1H-indole-2-carboxamideTrxR inhibitor D9 is a potent and selective inhibitor of thioredoxin reductase (TrxR), with an EC50 of 2. 8 nM. TrxR inhibitor D9 has the capability to inhibit tumor proliferation both in vitro and in vivo. Product information CAS Number: 1527513 89 8 Molecular Weight: 597. 44 Formula: C25H21AuOPS Chemical Name: 1 ethynyl 4 methoxybenzene diphenyl(thiophen 2 yl)phosphane gold Smiles: [Au]. COC1C=CC(=CC=1)C#C. C1=CC=C(S1)P(C1C=CC=CC=1)C1C=CC=CC=1