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Diclofenac potassium - CAS# 15307-81-0 551 Chemical Name: N-(1-cyclohexylpiperidin-4-yl)-2-(4-isopropyl-1

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Description

Chemical Name: N-(1-cyclohexylpiperidin-4-yl)-2-(4-isopropyl-1

Smiles: CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CC1=CC=CC=C1)C(=O)OCCOCCOCCOCCNC(=O)CO/N=C1\CCC(C)(C)C(C=C/C(/C)=C/C=C/C(/C)=C/C(O)=O)=C\1C |t:47|

ML264 is highly active (IC50=29 nM is a cell-based assay for proliferation of DLD-1 cells

The MAPK pathway is frequently disregulated in human cancers

Diclofenac potassium - CAS# 15307-81-0 551 Chemical Name: N-(1-cyclohexylpiperidin-4-yl)-2-(4-isopropyl-1Diclofenac potassium is a potent and nonselective anti inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1. 3 nM for human COX 1 and COX 2 in CHO cells, and 5. 1 and 0. 84 M for ovine COX 1 and COX 2, respectively. Diclofenac potassium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade. Product information CAS Number: 15307 81 0 Molecular Weight: 334. 24 Formula: C14H10Cl2KNO2 Chemical Name:

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