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Efficient non-viral reprogramming of myoblasts to stemness with a single small molecule to generate cardiac progenitor cells
InChiKey: RDSACQWTXKSHJT-UHFFFAOYSA-N
The pseudokinase domains of JAK2 and JAK3 are not part of the kinome screening panel
CAS Number: 657-24-9
p-nitro-Pifithrin-α Catalog No.:M23047-C Efficient non-viral reprogramming of myoblastsp nitro Pifithrin , a cell permeable cyclic analog of pifithrin , is an inhibitor of p53 activity . The p53 tumor suppressor gene product can induce apoptotic cell death and plays a dominant role in apoptosis, genomic stability, and inhibition of angiogenesis. The p53 has been considered to be an oncogene and the wild type gene product actually functions as a tumour suppressor gene. p53 mutations play an important role in the development of many
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