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IC87114 (5 µM) also inhibits polarized morphology and spreading of neutrophils
The inhibition of thromboxane synthase in platelets by KF 13218 is sustained after removal of the extracellular compound
Carbachol (500 ng) does not affect REM sleep but enhances wakefulness in the rat
VU0467485 (AZ13713945) shows selectivity for M4 over human and rat M1/2/3/5
3-Isomangostin phenylpyruvic acid IC87114 (5 µM) also inhibits3 Isomangostin, extracted from Garciniamangostana. L. shell, is a potent MutT homologue 1 (MTH1) inhibitor with an IC50 value of 52 nM. 3 Isomangostin would be an attractive chemical tool for the development of anticancer agents. Product information CAS Number: 19275 46 8 Molecular Weight: 410. 46 Formula: C24H26O6 Chemical Name: 5,9 dihydroxy 8 methoxy 2,2 dimethyl 7 (3 methylbut 2 en 1 yl) 2,3,4,6 tetrahydro 1,11 dioxatetracen 6 one Smiles:
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