DBCO-PEG4-Ahx-DM1 PEG4)-L-Lysine-PFP ester 90 µM and 1

90 µM and 1

Ginkgolide B at a dose of 300 μM also inhibits the superoxide production by PAF-acether-stimulated alveolar macrophages

SI-2 causes minimal acute cardiotoxicity based on a hERG channel blocking assay and an unappreciable chronic toxicity to major organs based on histological analyses

ML265: A potent PKM2 activator induces tetramerization and reduces tumor formation and size in a mouse xenograft model

DBCO-PEG4-Ahx-DM1 PEG4)-L-Lysine-PFP ester 90 µM and 1DBCO PEG4 Ahx DM1 is a drug linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO PEG4 Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor specific delivery. Product information Molecular Weight: 1297. 92 Formula: C68H89ClN6O17 Chemical Name: [(2R,