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Smiles: OC(C1CCNCC1)(C1C=CC=CC=1)C1C=CC=CC=1
InChiKey: VRHJBWUIWQOFLF-SQGQDMBVSA-N
CAS Number: 1108743-60-7
9 nM in KYSE70 and A549 cells
BMS-345541 hydrochloride Size:Solid 2 mg Smiles: OC(C1CCNCC1)(C1C=CC=CC=1)C1C=CC=CC=1BMS 345541 is a selective allosteric inhibitor of IKK (IC50 values are 0. 3 and 4. 0 M for IKK and IKK respectively). It attenuates LPS induced cytokine production in vitro and blocks NFB dependent transcription in mice. BMS 345541 also suppresses joint destruction in a mouse model of arthritis. Product information CAS Number: 547757 23 3 Molecular Weight: 291. 78 Formula: C14H18ClN5 Synonym: BMS345541 hydrochloride BMS 345541 hydrochloride BMS 345541
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