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Epub 2015 May 9
Solubility: DMSO: 100 mg/mL(136
BRN0123183
Fasudil Hydrochloride (50-100 μM
GDC-0941 dimethanesulfonate - CAS# 957054-33-0 Catalog No.:M10946-2 Epub 2015 May 9Pictilisib, also known as Pictrelisib, GDC 0941, RG7321 and GNE0941 , is an orally bioavailable, and is a potent small molecule thieno[3,2 d]pyrimidine inhibitor of the class I phosphatidylinositol 3 kinase (PI3K) isoforms p100alpha and p100delta with potential antineoplastic activity. GDC 0941 selectively binds to PI3K isoforms in an ATP competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol 3,4,5 trisphosphate
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