Pay in 4 interest-free payments of $20.00 Learn more
Ships within 48 hours · Estimated delivery Aug 13 - Aug 18
125(4):1692-702
This strategy preferentially targets primary Bcr/Abl(+) hematopoietic cells and exhibits enhanced in vivo activity
It incorporates an E3 ligase ligand plus a PEG4 linker with terminal carboxylic acid ready for conjugation to a target protein ligand It is part of a range of functionalized tool molecules for PROTAC R&D
It covalently binds to the cysteine 88 of ubiquitin receptor RPN13 in the 19S regulatory particle and inhibits proteasome function
Tenofovir alafenamide hemifumarate tegravir (MK-0518) 125(4):1692-702Tenofovir alafenamide (TAF, GS 7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV 1 infection. Product information CAS Number: 1392275 56 7 Molecular Weight: 1069. 00 Formula: C46H62N12O14P2 Synonym: Tenofovir alafenamide fumarate (2: 1) Chemical Name: