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Dyrk1B/A-IN-1
CAS Number: 1374743-00-6
InChi: InChI=1S/C18H13BrN4O/c1-2-4-17(24)22-14-7-8-16-15(10-14)18(21-11-20-16)23-13-6-3-5-12(19)9-13/h3
PubMed PMID: 20981342
RO-9187 1470 (methanesulfonate) Dyrk1B/A-IN-1RO 9187 is a potent inhibitor of HCV virus replication in the replicon system (IC(50) = 171 + 12 nM; CC(50) >1 mM). RO 9187 is an excellent substrate for deoxycytidine kinase and is phosphorylated with efficiencies up to 3 fold higher than deoxycytidine. RO 9187 is a new class of antiviral nucleosides with promising preclinical properties as potential medicines for the treatment of HCV infection. Product information CAS Number: 876708 03 1 Molecular
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