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In the mouse xenograft models using subcutaneously transplanted UM-UC-14 and MGHU3
EC(50) = 490 nmol/L)
CAS Number: 2375421-09-1
Vascular endothelial growth factor (VEGF) receptor-2 antagonists inhibit VEGF- and basicfibroblast growth factor-induced angiogenesis in vivo and in vitro
Almotriptan Malate Catalog No.:M9101-2 In the mouse xenograft modelsAlmotriptan Malate is a triptan drug discovered and developed by Almirall for the treatment of heavy migraine headache. Almotriptan is a Serotonin 1b and Serotonin 1d Receptor Agonist. Binding of the drug to the receptor leads to vasoconstriction of the cranial blood vessels and thus affects the redistribution of cranial blood flow. Almotriptan significantly increases cerebral blood flow and reduces blood flow through extracerebral cranial vessels.
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