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Vps34-IN-2 - CAS# 1523404-29-6 ide-Piperazine-PEG3-COOH InChi: InChI=1S/C28H38N8O5/c1-20-19-35(14-17-41-20)28(38)30-22-9-7-21(8-10-22)25-31-26(34-12-15-40-16-13-34)23-18-29-36(27(23)32-25)11-5-3-2-4-6-24(37)33-39/h7-10

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Description

InChi: InChI=1S/C28H38N8O5/c1-20-19-35(14-17-41-20)28(38)30-22-9-7-21(8-10-22)25-31-26(34-12-15-40-16-13-34)23-18-29-36(27(23)32-25)11-5-3-2-4-6-24(37)33-39/h7-10

Chemical Name: (S)-3-(4-methoxyphenyl)-N-((S)-1-((S)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)propanamido)propanamide

InChi: InChI=1S/C25H38O4/c1-5-22(26)28-17-11-13-24(3)16(15-17)7-8-18-19-9-10-21(29-23(27)6-2)25(19

17S)-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9

Vps34-IN-2 - CAS# 1523404-29-6 ide-Piperazine-PEG3-COOH InChi: InChI=1S/C28H38N8O5/c1-20-19-35(14-17-41-20)28(38)30-22-9-7-21(8-10-22)25-31-26(34-12-15-40-16-13-34)23-18-29-36(27(23)32-25)11-5-3-2-4-6-24(37)33-39/h7-10Vps34 IN 2 is a novel, potent and selective inhibitor of Vps34 with IC50s of 2 and 82 nM on the Vps34 enzymatic assay and the GFP FYVE cellular assay, respectively. Vps34 IN 2 shows antiviral activity against SARS CoV 2 (IC50 of 3. 1 M), HCoV 229E (IC50 of 0. 7 M) and HCoV OC43. Product information CAS Number: 1523404 29 6 Molecular Weight: 402. 41 Formula: C18H25F3N4O3 Chemical Name: (S) 9 (3 methyl 2 oxobutyl) 2 ((R) 3 methylmorpholino) 8

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