A-317491 sodium salt hydrate thalin Smiles: C[C@H]1C[C@@H]2[C@H]([C@@H](O)C[C@@]3(C)[C@H]2CC[C@]3(O)C(=O)CO)[C@@]2(C)C=CC(=O)C=C21

Smiles: C[C@H]1C[C@@H]2[C@H]([C@@H](O)C[C@@]3(C)[C@H]2CC[C@]3(O)C(=O)CO)[C@@]2(C)C=CC(=O)C=C21

Bardoxolone blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0

5-dichloro-N-(2-methyl-4-nitrophenyl)-benzenesulfonamide

Formula: C11H11F3N2O3

A-317491 sodium salt hydrate thalin Smiles: C[C@H]1C[C@@H]2[C@H]([C@@H](O)C[C@@]3(C)[C@H]2CC[C@]3(O)C(=O)CO)[C@@]2(C)C=CC(=O)C=C21A 317491 sodium salt hydrate is a non nucleotide P2X3 and P2X2 3 receptor antagonist, which inhibits calcium flux mediated by the receptors. IC50 value: Target: P2X2 3 receptor It is known that P2X3 and P2X2 3 receptors stimulate the pronociceptive effects of ATP upon activation. Studies indicate that the P2X3 receptor is implicated in both neuropathic and inflammatory pain. P2X3 receptor is a promising target for therapeutic intervention in cancer