ICA-121431 TAC K858 (5 μM) induces mitotic

K858 (5 μM) induces mitotic cell death in cancer cells but not in normal cells

E3 Ligase Ligand-Linker Conjugates 58

[2] Bepotastine besilate (10 mg/kg) inhibits scratching induced by an intradermal injection of histamine (100 nmol/site)

CAS Number: 90458-75-6

ICA-121431 TAC K858 (5 μM) induces mitoticICA 121431 is a potent, selective inhibitor of the human Nav1. 3 and Nav1. 1 voltage gated sodium channels (IC50 = 19 nM) with little or no activity against human Nav1. 5 or Nav1. 7 channels. Voltage gated sodium channels initiate action potentials in brain neurons, and sodium channel blockers are used in therapy of epilepsy. Product information CAS Number: 313254 51 2 Molecular Weight: 449. 55 Formula: C23H19N3O3S2 Chemical Name: 2,2 diphenyl N {4