Pay in 4 interest-free payments of $25.00 Learn more
Ships within 48 hours · Estimated delivery Aug 4 - Aug 9
KU-0063794 at 30 nM is sufficient to rapidly ablate S6K1 activity by blocking the phosphorylation of the hydrophobic motif (Thr389) and subsequently the phosphorylation of the T-loop residue (Thr229)
Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties
11-dihydroxy-3
4R)-2-aminooctadecane-1
Raloxifene 6-glucuronide Catalog No.:M13237-10 KU-0063794 at 30 nM isRaloxifene 6 glucuronide is a primary metabolite of Raloxifene. Raloxifene 6 glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6 glucuronide binds to estrogen receptor with an IC50 of 290 M. Raloxifene is a selective and nonsteroidal estrogen receptor modulator. Raloxifene activates TGF3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element containing vitellogenin promoter expression. Product