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and concomitantly suppresses the activation of the downstream signaling molecules such as Akt and Erk1/2 mitogen-activated protein kinase (MAPK)
Lanabecestat displays pM potency in primary neuron cultures from mice and guinea pigs and in SH-SY5Y cells over-expressing AβPP (IC50=610 pM
InChiKey: LZJRNLRASBVRRX-ZDUSSCGKSA-N
Sufugolix exhibits more than 3- and 2000-fold selectivity for the human receptor over the monkey and rat receptors
L-Leucyl-L-alanine Catalog No.:M30846-C and concomitantly suppresses the activationL Leucyl L alanine is a simple dipeptide composed of L leucine and L alanine. Product information CAS Number: 7298 84 2 Molecular Weight: 202. 25 Formula: C9H18N2O3 Chemical Name: (2S) 2 [(2S) 2 amino 4 methylpentanamido]propanoic acid Smiles: CC(C)C[C@H](N)C(=O)N[C@@H](C)C(O)=O InChiKey: HSQGMTRYSIHDAC BQBZGAKWSA N InChi: InChI=1S C9H18N2O3 c1 5(2)4 7(10)8(12)11 6(3)9(13)14 h5 7H,4,10H2,1 3H3,(H,11,12)(H,13,14) t6 ,7 m0 s1 Technical Data Appearance:
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