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Flavopiridol (Alvocidib) cadesine is an inhibitor of non-mammalian

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Description

is an inhibitor of non-mammalian and mammalian β-glucosidase

PubMed PMID: 26061247

17S)-33-((2-(diethylamino)ethyl)sulfonyl)-17-hydroxy-6-isopropyl-7

chrysin is reported to be an aromatase inhibitor in vitro

Flavopiridol (Alvocidib) cadesine is an inhibitor of non-mammalianAlvocidib is a synthetic N methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin dependent kinases (CDKs) and by down regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity. Check for active clinical trials or closed clinical

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