ATR inhibitor 2 oxamide Tromethamine Smiles: CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)NC

Smiles: CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)NC

34R)-18-hydroxy-34-[(1S)-1-hydroxyethyl]-23

Smiles: O=C(COC1C=CC(Cl)=CC=1)NC1CCC(CC1)NC(=O)COC1C=CC(Cl)=CC=1

Formula: C6H14Cl2N4O2

ATR inhibitor 2 oxamide Tromethamine Smiles: CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)NCATR inhibitor 2 is an ATP competitive, orally active, and selective ATR inhibitor, with a Ki of <150 pM. ATR inhibitor 2 potently inhibits ATR driven phosphorylated checkpoint kinase 1 (Chk1) phosphorylation with an IC50 of 8 nM. Antitumor activity. Product information CAS Number: 1613191 99 3 Molecular Weight: 541. 55 Formula: C25H29F2N9O3 Chemical Name: 2 amino 6 fluoro N (5 fluoro 4 {4 [4 (oxetan 3 yl)piperazine 1 carbonyl]piperidin 1 yl}pyridin 3