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26-12-5-2-6-13-26)14-8-16-31-17-19-32(20-18-31)30-22-24-9-7-15-29-21-24/h1-7
Formula: C8H11NO4
Berberine (10-80 μM) suppresses cyclin B1
Chemical Name: (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1
RG-12525 Catalog No.:M18811-C 26-12-5-2-6-13-26)14-8-16-31-17-19-32(20-18-31)30-22-24-9-7-15-29-21-24/h1-7RG 12525 is a a specific, competitive and orally effective antagonist of the peptidoleukotrienes, LTC4, LTD4 and LTE4, inhibiting LTC4 , LTD4 and LTE4 inducd guinea pig parenchymal strips contractions, with IC50s of 2. 6 nM, 2. 5 nM and 7 nM, respectively; RG 12525 is also a peroxisome proliferator activated receptor gamma (PPAR gamma) agonist with IC50 of appr 60 nM and a potent inhibitor of CYP3A4, with a Ki value of 0. 5 M. Product information CAS