![Tacrolimus Catalog No.:M7733-10 Chemical Name: N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M7733_1619054148.gif?v=1629174789)
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Chemical Name: N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea
induces DNA double-strand breaks quantified as S139 phosphorylated histone foci (γ-H2AX) and Comet tails induced in MDA-MB-231 cells
CAS Number: 3599-32-4
Bay 43-9006 or a combination of both give similar results in terms of measurement of external tumor size (around 58% growth reduction compare with control tumors)
Tacrolimus Catalog No.:M7733-10 Chemical Name: N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]ureaTacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T lymphocyte signal transduction and IL 2 transcription. Immunosuppressive properties. Product information CAS Number: 104987 11 3 Molecular Weight: 804. 02 Formula: C44H69NO12 Synonym: FK 506 FK 506 FK506 fujimycin Prograf Protopic Advagraf Astagraf XL Related CAS Number: 109581 93 3