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Paolieri F
Treatment of the mitotic cells with BMS-345541 results in precocious cyclin B1 and securin degradation
9(8):756-76
is a potent and selective antagonist for the prostaglandin E2 receptor subtype EP2
CHIR99021 HCl - CAS# 1797989-42-4 THP Paolieri FCHIR99021 HCl, CAS No. 1797989 42 4, also known as CT99021, is a glycogen synthase kinase 3 (GSK3) inhibitor that has antiproliferative activity in vitro and in vivo. CHIR99021 inhibits GSK 3 with IC50 at 7 nM. In a series of carcinoma cell lines, the IC50 of CHIR99021 for proliferation is about 10M. Product information CAS Number: 1797989 42 4 Molecular Weight: 501. 80 Formula: C22H19Cl3N8 Synonym: CT 99021 Related CAS Number: 252917 06 9 (free base)
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