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InChi: InChI=1S/C21H25N3O3/c1-12-19(24-20(21(22)27)13(2)23-12)17-9-7-16(8-10-17)15-5-3-14(4-6-15)11-18(25)26/h7-10
CAS Number: 2313525-20-9
IPI-9119 is an orally active
intravenous injection) inhibits [3H]AZD2184 binding (1 nM) in a concentration-dependent manner
RORγt agonist 1 Catalog No.:M30089-C InChi: InChI=1S/C21H25N3O3/c1-12-19(24-20(21(22)27)13(2)23-12)17-9-7-16(8-10-17)15-5-3-14(4-6-15)11-18(25)26/h7-10RORt agonist 1 (compound 14) is a potent, orally bioavailable RORt agonist with an EC50 of 20. 8 nM. RORt agonist 1 showes high metabolic stability, improved aqueous solubility and excellent mouse PK profile. RORt agonist 1 is a potential candidate of RORt agonist for cancer immunotherapy. Product information CAS Number: 2377378 89 5 Molecular Weight: 545. 45 Formula: C24H17F6NO5S Chemical Name: 2 {6 [3 (difluoromethoxy) 5 fluorophenyl] 1 [3
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