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5 μM against all other PDE isoforms
Butein potently inhibits cAMP-specific phosphodiesterase (type IV) activity with an IC50 of 10
Chemical Name: potassium 4-{[(1R
4 L/kg and a terminal T1/2 of approximately 2 h
GGTI-2418 14533 5 μM against all otherGGTI 2418 is a highly potent, competitive, and selective geranylgeranyltransferase I (GGTase I) inhibitor. GGTI 2418 inhibits GGTase I and FTase activities with IC50s of 9. 5 nM and 53 M, respectively. GGTI 2418 also increases p27(Kip1) and induces significant regression of breast tumors. Product information CAS Number: 501010 06 6 Molecular Weight: 441. 52 Formula: C23H31N5O4 Chemical Name: (2S) 2 {[(2S) 2 benzyl 4 [(5 methyl 1H imidazol 4 yl)methyl]
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