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11-pentaene-11-carboxamide
Chemical Name: 1-(4-(4-(dimethylamino)piperidine-1-carbonyl)phenyl)-3-(4-(4
CAS Number: 193620-69-8
disrupts microtubule organization in cells
MK591 xacin(DU 6859A) 11-pentaene-11-carboxamideQuiflapon, also known as MK 0591, is a potent and selective 5 Lipoxygenase activating protein (FLAP) inhibitor. MK 0591 is also a potent inhibitor of leukotriene (LT) biosynthesis in intact human and elicited rat polymorphonuclear leukocytes (PMNLs) (IC50 values 3. 1 and 6. 1 nM, respectively) and in human, squirrel monkey, and rat whole blood (IC50 values 510, 69, and 9 nM, respectively). MK 0591 has a high affinity for 5 lipoxygenase activating
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