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UPGL00004 is a potent allosteric glutaminase C (GAC) inhibitor (IC50=29 nM
53(26):3637-3640
ENMD-1198 (0-5 μM
It acts by preventing lipid peroxidation
Methyltetrazine-Sulfo-NHS ester sodium 23-2 UPGL00004 is a potent allostericMethyltetrazine Sulfo NHS ester (sodium) is an alkyl ether based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 1821017 46 2 Molecular Weight: 429. 34 Formula: C15H12N5NaO7S Chemical Name: sodium 1 ({2 [4 (6 methyl 1,2,4,5 tetrazin 3 yl)phenyl]acetyl}oxy) 2,5 dioxopyrrolidine 3 sulfonate Smiles: [Na+]. CC1=NN=C(N=N1)C1=CC=C(CC(=O)ON2C(=O)C(CC2=O)S([O ])(=O)=O)C=C1 InChiKey: DSVIJQIFAWOGME UHFFFAOYSA M