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Smiles: COC1C=CC(=CC=1)OCC1C2=CC(OC)=C(C=C2CCN1C(=O)C1=CC(Cl)=CC=C1)OC
June 14¨C17
Molecular Weight: 509
KN-62 is found to be a potent antagonist in a functional assay
Alda-1 - CAS# 349438-38-6 size:2mg solid Smiles: COC1C=CC(=CC=1)OCC1C2=CC(OC)=C(C=C2CCN1C(=O)C1=CC(Cl)=CC=C1)OCAlda 1, CAS No. 349438 38 6, is a potent and selective Aldehyde Dehydrogenase 2 Agonist. Alda 1 reverses alcohol induced hepatic steatosis and cell death in mice. Alda 1 inhibits atherosclerosis and attenuates hepatic steatosis in apolipoprotein E knockout mice. Alda 1 reduces cerebral ischemia reperfusion injury in rat through clearance of reactive aldehydes. Pharmacological activation of ALDH2 by Alda 1 reversed alcoholic steatosis and apoptosis
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