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a p38 mitogen-activated protein-kinase inhibitor
BX-471 exhibits 250-fold selectivity for CCR1 over CCR2
Cariprazine stimulates inositol phosphate (IP) formation with a high potency (pEC50 8
InChi: InChI=1S/C22H20N4O/c23-17-8-11-21-20(14-17)22(26-15-25-21)24-13-12-16-6-9-19(10-7-16)27-18-4-2-1-3-5-18/h1-11
Epirubicin - CAS# 56420-45-2 Catalog No.:M9815-2 a p38 mitogen-activated protein-kinase inhibitorEpirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. Similarly to other anthracyclines, epirubicin acts by intercalating DNA strands. Intercalation results in complex formation which inhibits DNA and RNA synthesis. It also triggers DNA cleavage by topoisomerase II, resulting in mechanisms that lead to cell death.
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