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Smiles: CC1C=CC(=CC=1)S(=O)(=O)NC(=O)NCCCC
18)19)8-13(7-11)24-3/h4-10H
2017 May 15
2020 Aug 21
CGI-1746 - CAS# 910232-84-7 AA-94 Smiles: CC1C=CC(=CC=1)S(=O)(=O)NC(=O)NCCCCCGI1746 is a small molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto and transphosphorylation steps necessary for enzyme activation. Product information CAS Number: 910232 84 7 Molecular Weight: 579. 69 Formula: C34H37N5O4 Synonym: CGI1746 CGI 1746 Chemical Name: 4 tert butyl N [2 methyl 3 (4 methyl 6 {[4
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